Finding peace with Serotoned

What Are Adaptogens: The Science, Benefits, And Side Effects

Sero-02 contains 15 adaptogens all targeted at reducing anxiety, panic attacks, and insomnia.

Adaptogens are herbs, roots, plants, and fungi that help improve your body’s ability to remain calm and resist future anxiety.


There is no end to what causes us anxiety today. By including adaptogens in your routine you can protect yourself from the extreme hormonal ups and downs caused by stress.

Using adaptogens isn’t new!

People have been using herbs and natural remedies like ashwagandha, ginseng, and rhodiola for their stress-reducing and cognitive-enhancing properties for thousands of years.

The term “adaptogens” was first used in 1947.

Since then, the function of adaptogens has been well-researched and accepted by many scientists and doctors as an alternative or an enhancement to modern Western medicine.

All biological enhancements or adaptogens carry their list of side effects and drug interactions. It’s important you know what you’re putting into your body and whether there are risks involved.



What Are Adaptogens?

Adaptogens are a group of specific herbs, roots, plants, and fungi that help the body cope with anxiety on a biological level.

Adaptogens help improve the body’s nonspecific resistance to anxiety reactions.

Adaptogens work on the hypothalamic-pituitary-adrenal (HPA) axis.

This means they work on the relationship between the hypothalamus, the pituitary gland, and the adrenal glands to reduce anxiety levels and raise the body’s resistance to anxiety and stress.


How Does My Body React to Anxiety?

  1. You’re emotionally triggered by an external factor to panic, be anxious, or be fearful and this stimulates your hypothalamus.

  2. Your hypothalamus releases a hormone called CRH (corticotropin-releasing hormone) to the pituitary gland. 

  3. Your pituitary gland responds by releasing a hormone called ACTH (adrenocorticotropic hormone).

  4. The ACTH signals to the adrenal glands on top of your kidneys to release cortisol and adrenaline.

  5. The adrenaline and cortisol put your body into hyper-aware survival mode. (1)


How Do Adaptogens Affect My Anxiety?

Many adaptogens directly affect the amount of cortisol produced by the body. Some adaptogens raise the levels of cortisol and others reduce it.

That’s why you need to know exactly what you’re putting into your body.

It would be silly to take a supplement with Schisandra chinensis (Turcz.) Baill (also known as the Chinese magnolia vine or five-flavor berry) in it right before bed because this adaptogen stimulates cortisol production.

You wouldn’t have restful sleep at all!

However, if you suffer from insomnia or anxiety, taking a supplement with an adaptogen that reduces cortisol before bed would calm you and improve your sleep.

Adaptogens such as ashwagandha and rhodiola suppress and lower cortisol levels.


What Adaptogens Are In Sero-02?

Sero-02 is designed to help calm you, reduce your anxiety and fatigue, improve your quality of sleep, and help you live a life better adapted to the stressful situations you face.

Here are the adaptogens in Sero-02 and how they can help you:

  1. Ashwagandha Root Extract: reduces cortisol levels (your stress hormone)

  2. Chamomile Powder: helps reduce inflammation, body aches, and anxious feelings

  3. Lemon Balm Powder: helps reduce anxiety and gut inflammation

  4. Holy Basil Extract: helps reduce cortisol levels and improves brain (cognitive) function

  5. Gotu Kola: improves the quality of sleep and cognitive clarity

  6. St. John's Wort Extract: helps reduce feelings of depression, anxiety, and panic

  7. Black Pepper Fruit Extract: improves immunity and absorption of other adaptogens

  8. Rhodiola Rosea Root Extract: helps reduce cortisol, depression, stress, and fatigue

  9. Saffron Extract: improves the mood and helps fight depression

What Makes An Adaptogen, An Adaptogen?

Not all herbs, roots, plants, and mushrooms are considered adaptogens. Natural substances need to meet three very specific conditions to be called adaptogens. (2)

  1. Help the body cope with current anxiety.

  2. Be nontoxic to humans at recommended dosages.

  3. Help the body remain stable in a state of homeostasis adapted to better cope with future stress.

All adaptogens in Sero-02 meet these conditions to help you live in a stressful world.

How Do Adaptogens Affect And Benefit The Body?

Your body fluctuates or moves above and below “normal.” You want to be as close to the homeostatic line as possible because that means your body is stable.

Your body ideally exists in homeostasis. Homeostasis means being in an equal, stable, and balanced state. When your glands release hormones, they push the body out of homeostasis.

1. Experience Anxiety

A huge increase in cortisol puts the body into its Alarm Phase and moves it out of homeostasis or stability.

During the Alarm Phase, your body experiences a stress response and shock.

Using an adaptogen makes the huge drop away from homeostasis a smaller one, making the return to homeostasis shorter and easier.

2. Enter Fight Or Flight Mode

During the Resistant Phase, your body is fighting anxiety, whether they’re an internal or external form of stress. The more anxiety your body experiences, the higher your stress response is.

Using an adaptogen makes the rise in the stress response a slower one and stops it from getting as high. This is because some adaptogens reduce the amount of cortisol your body produces.

Living in this state is exhausting and dangerous as it wears away at your body and mind.

3. Coming Down From The Stress High

When your body has dealt with the anxiety, the stress response drops quickly and the body falls into the Exhaustion Phase where it drops below homeostasis. This is when you feel fatigued and your energy is spent.

Using an adaptogen makes the “come down” from stress a much gentler experience.

The adaptogen also has a stimulating effect on your homeostasis to prevent you from falling into the Exhaustion Phase.

This is how the adaptogen protects you.

It adapts your body by decreasing your sensitivity to stressors and increasing your nonspecific resistance to stress.

Adaptogens bring your body into a new stable state.

Click here for a video explanation of this diagram.




FAQs On Adaptogens…

Can anyone take adaptogens?

Everyone’s bodies react differently to substances they eat or drink. You should always check with your doctor before taking supplements especially if:

  1. You’re pregnant or breastfeeding

  2. You’re diabetic (type 1 and type 2)

  3. You have high or low blood pressure

  4. You have ulcers

  5. You suffer from autoimmune disorders that affect the hormones.

  6. You’re preparing for surgery or have recently undergone surgery.

    Do adaptogens have side effects?

    The side effects of adaptogens depend on the person. Some people have allergies to specific adaptogens and should look for them before taking any supplements.

    People who have sensitive stomachs, suffer from IBS, or severe acid reflux may experience nausea, diarrhea, and stomach cramps if they take adaptogens on an empty stomach.

    How do adaptogens interact with medication?

    Adaptogens affect the body by increasing or decreasing hormonal reactions to stressors. This includes affecting cortisol and adrenaline levels.

    If you take medications, always check with your prescribing doctor before taking any supplements. (4)


    Wrapping Up On The Benefits Of Adaptogens…

    There are many benefits to taking adaptogens. Adaptogens help your body adapt and cope with anxiety by adapting your experience of stress and your reaction to it.

    Knowing what you put into your body is very important because adaptogens can increase or suppress hormonal reactions.

    If you’re looking for a supplement to help calm your anxiety and improve your sleep, then Sero-02 is the right one for you.


    Our Recommended Reading:

    1: Endocrine Society, 2022, Adrenal Hormones. Patient Care.

    2: UCLA Fielding School of Public Health. (2022). What are adaptogens and the possible benefits of taking them?

    3: Panossian, A., & Wikman, G. (2010). Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity. Pharmaceuticals (Basel, Switzerland), 3(1), 188–224.

    4: Cleveland Clinic. (2022). Adaptogens. Drugs, Devices, and Supplements.



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